Boost Cellular Health, Detoxify the Body, and Strengthen Your Immune System

Major Autohemotherapy (MAH) ozone therapy is a gentle treatment that involves drawing a small amount of blood ( upto 200 ml) into a sterile, ozone- resistant container. A blood thinner (heparin or Sodium Citrate) is added and a precise concentration of medical-grade ozone gas (a mixture of oxygen and ozone) is gently re-infused back into the bloodstream. It is a gentle treatment that helps improve oxygen use, circulation, and immune balance.

The ozone reacts immediately with components in the blood, especially red blood cells, proteins, and lipids. It induces controlled oxidative stress that activates antioxidant defences, enhances oxygen metabolism, stimulates immune messengers (like cytokines), and improves detox pathways, circulation, and mitochondrial function.

To prevent clotting in the collection system, we use a gentle anticoagulant—either heparin (derived from animal sources) or sodium citrate.

It’s essential that you inform us of any known allergies—particularly to heparin, pork products, citrate, or sulphites—as these may cause reactions ranging from local irritation and bruising to rare but serious allergic responses like hives, swelling, or difficulty breathing.

If you have a history of heparin- induced thrombocytopenia (HIT) or severe bleeding disorders, our team may use sodium citrate instead, which is widely considered safer due to its rapid clearance and lower risk of systemic effects.

Before the Session

⚪️ Hydration

• Drink plenty of water (at least 2–3 glasses within a couple of hours before your appointment).

• Good hydration makes it easier to draw blood and supports circulation.

⚪️ Eat Light

• Have a light meal or snack 1–2 hours before.

• Avoid coming on an empty stomach (prevents dizziness) and avoid heavy, fatty meals right before treatment.

⚪️ Medications & Supplements

• Continue your regular medications unless advised otherwise.

• Some anticoagulants (blood thinners) may need special consideration — always disclose these to the practitioner.

• Avoid high-dose vitamin C (over 1,000 mg) just before the session, as it can neutralize ozone’s effects.

⚪️ Rest & Lifestyle

• Be well-rested. Fatigue and dehydration can increase the chance of feeling lightheaded.

• Avoid alcohol on the day of treatment.

• Limit caffeine directly before, as it may constrict veins.

During the Session

Wear comfortable clothing with sleeves that roll up easily.

Relax — the process feels similar to donating blood, with infusion taking from 30–90 minutes.

After the Session

⚪️ Hydration Again – Drink more water to help flush byproducts and support circulation.

⚪️ Light Activity – Gentle movement is fine; avoid strenuous exercise immediately after your first few sessions.

⚪️ Possible Mild Effects – Some people may feel temporary fatigue, slight flu-like feelings, or mild detox symptoms, which usually pass quickly.

⚪️ Nutrition – Eating antioxidant-rich foods (fruits, vegetables, healthy fats) supports the therapy’s benefits.

Everyone’s blood is different but your session can last from 30 minutes to 90 minutes as it depends on how many passes you are having.

Claimed Benefits of MAH Ozone Therapy

🔵Improved Oxygen Delivery

Claimed to enhance oxygen release to tissues by altering red blood cell flexibility and metabolism.

🔵Immune System Support

It is said to stimulate immune cells and improve the body’s ability to fight infections, viruses, and inflammation.

🔵Anti-inflammatory Action

Reduces oxidative stress and inflammation by activating the body’s own antioxidant systems (e.g. glutathione). It can help to modulate inflammatory responses in conditions such as arthritis or autoimmune issues.

🔵Antiviral & Antibacterial Effects

Ozone has strong disinfectant properties that may help reduce chronic infections.

🔵Improved Circulation

By reducing blood viscosity and improving microcirculation.

🔵Mitochondrial Function and Energy Boost

Practitioners claim it can stimulate cellular energy production (ATP), potentially helping with fatigue, brain fog or chronic conditions.

🔵Detoxification Support

Believed to aid in the breakdown and elimination of toxins and metabolic waste

🔵Wound Healing and Tissue Repair

Ozone is sometimes used to promote healing in chronic wounds and chronic infections.

🔵Adjunctive Cancer Care (alternative/experimental use)

Some proponents claim it may improve quality of life or reduce side effects of chemotherapy or radiation.

🔵Anti-aging and Wellness

Marketed as enhancing vitality, resilience, and overall wellbeing

The number of MAH (Major Autohemotherapy) ozone therapy sessions needed depends a lot on the person’s health goals and condition being treated. There isn’t a “one size fits all,” but here’s what is typically recommended:

⚪️General wellness / preventative use: Some people do a short course of 3–5 sessions or periodic maintenance sessions (e.g., once a month).

⚪️Chronic conditions (fatigue, autoimmune, infections, circulatory issues): Usually a course of 8–12 sessions, often given 1–2 times per week. After that, sessions may be spaced out for maintenance (e.g., once every few weeks or months).

⚪️Acute infections or recovery support (e.g., post-viral, Lyme, long COVID): Often a more intensive schedule of 2–3 sessions per week initially, then tapering down as symptoms improve.

⚪️Maintenance / ongoing support: Once a person feels better, many practitioners suggest a monthly or bi-monthly session to sustain benefits.

With Major Autohemotherapy (MAH), benefits can be both immediate and cumulative, depending on the individual and the condition being treated.

Everyone responds differently to MAH Ozone , but here is a general guide:

⚪️After 1–2 sessions

Some people may notice:

• More energy and mental clarity

• Better sleep

• A sense of wellbeing or lightness

Others may not feel much at first but this is normal.

⚪️After 3–6 sessions

Most people may start to notice clearer changes such as:

• Reduced inflammation or pain

• Faster recovery from infections

• Improved stamina and vitality

• Less brain fog

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⚪️After a full course (6–12+ sessions)

More stable improvements are common, especially for long-term health issues like:

• Chronic fatigue

• Autoimmune conditions

• Lyme disease or long COVID

• Circulatory problems

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⚪️Long-term (maintenance therapy)

Some clients choose a top-up session every 4–6 weeks to maintain results, especially for chronic conditions.

Things to Remember

• Benefits may build gradually, especially if your health concerns are long-standing.

• Some people feel a short “detox” response (mild fatigue, headache, or flu-like symptoms). This usually passes within 24–48 hours.

• Staying hydrated, eating well, and resting will support your results.

⚪️ Pregnant or breastfeeding individuals

⚪️Those with G6PD deficiency

⚪️Hyperthyroidism

⚪️Bleeding or Blood Clotting Disorders

⚪️Individuals with extreme respiratory or cardiac vulnerability, or those unable to tolerate oxidative procedures

⚪️Allergy to Ozone

⚪️Allergy to Heparin or Sodium Citrate

⚪️Alpha Gal syndrome (due to the use of heparin)

⚪️Recent Stroke or Heart Attack

⚪️Alcohol Intoxication

⚪️Organ Transplant recipient

It’s generally not recommended to start with a 10-pass ozone therapy session as your very first MAH treatment. Here’s why:

⚖️ Differences between MAH single pass and 10-pass

⚪️MAH (single-pass autohemotherapy): Your blood is withdrawn, mixed with ozone, and reinfused — usually once per session. It’s gentler and allows your body to adapt to the oxidative stress and immune stimulation.

⚪️10-pass (OHT – ozone high-dose therapy): This repeats the MAH process up to 10 times in one sitting. It delivers a much higher ozone dose and is significantly more intensive.

🚫 Why not start with 10-pass?

⚪️Tolerance & safety: The body needs time to adjust. Starting too high can cause strong detox reactions, fatigue, or “Herxheimer reactions” (temporary worsening of symptoms).

⚪️Screening: Practitioners usually want to see how you respond to a 1-5 pass MAH before escalating.

✅ Common approach

⚪️Begin with a standard 1-3 or a 5 pass for a few sessions depending on your history and fitness level.

⚪️If tolerated well, and if your goals or health condition suggest it could be useful, your practitioner may then recommend moving to multi-pass sessions.

Occasionally a Herxheimer reaction, sometimes referred to as a “die off” or “healing crisis" , can occur as your body processes the sudden release of endotoxins from killed pathogens. The body struggles temporarily to process and eliminate this sudden toxic load which leads to a Herxheimer reaction.

It is a short-term reaction that can happen when the body is detoxifying or killing off harmful microbes more quickly than it can eliminate their byproducts. It is not guaranteed that this won’t happen and therefore we suggest that anyone who is unsure to get in touch with us to seek further advice and guidance.

What happens

• When bacteria, viruses, fungi, or other pathogens are killed, they release toxins and inflammatory molecules.

• The immune system reacts strongly to this sudden release.

• The body temporarily feels worse before it feels better.

📌 Common symptoms

• Flu-like feelings (chills, fever, sweating, body aches)

• Headache

• Fatigue, brain fog, headache

• Muscle or joint aches

• Digestive upset (nausea, diarrhea, bloating, occasionally vomitting)

• Worsening of existing symptoms for a short period

• Skin reactions: rashes, itching, acne-like eruptions, worsening of existing lesion

⏳ Duration

These symptoms usually emerge within hours to a few days of treatment and typically resolve within a few days to about a week, though longer-lasting symptoms are occasionally reported but the symptoms will settle as the body clears the toxins.

⚠️ Why it matters with ozone therapy

Ozone can kill pathogens and stimulate detox pathways. For some people, especially if they have chronic infections or high toxic load, this can trigger a Herxheimer reaction which is why many practitioners start with lower doses before considering stronger treatments, so the body can adapt gradually.

To ease symptoms and support recovery:

⚪️Hydration: Drink plenty of water (electrolyte-rich fluids are ideal)

⚪️Rest: Allow time for your body to recover

⚪️Binders: Activated charcoal or similar supplements may help absorb toxins

⚪️Gentle Heat: Saunas, baths, Epsom salt soaks, or light exercise can support detox

⚪️Balanced Nutrition: Antioxidant-rich foods and probiotics support detox pathways

Ozone itself is very short-lived in the body — it reacts almost instantly once it’s introduced into the blood during a MAH (Major Autohemotherapy) ozone therapy session. Here’s what happens:

⏱️ Timeline of ozone in the body

• Seconds: Ozone (O₃) immediately reacts with components in the blood (antioxidants, fatty acids, amino acids).

• Minutes: It breaks down into ozonides and peroxides (reactive oxygen species). These are more stable and act as messengers in the body.

• Hours to days: These compounds trigger beneficial biological effects — improved oxygen delivery, immune modulation, anti-inflammatory effects, and mild hormetic oxidative stress that stimulates antioxidant defenses.

A G6PD test is recommended and a requirement in certain people because ozone is a strong oxidative therapy that produces oxidative stress that can severely damage red blood cells in people with low G6PD, leading to haemolytic anaemia (red blood cell breakdown).

People who should have a G6PD test before ozone therapy:

• People of ethnic groups with higher prevalence of G6PD deficiency.

• Anyone with a known family history of G6PD deficiency.

• People with unexplained hemolytic anemia in their history.

• Cancer patients.

• People with chronic illnesses who may not know their G6PD status

Yes, there are important contraindications. While ozone therapy is promoted for various conditions, it’s not suitable for everyone due to potential risks.

Absolute Contraindications

These are situations where MAH should not be carried out under any circumstances:

⚪️G6PD deficiency

Why: Red blood cells are highly sensitive to oxidative stress. Ozone can cause hemolysis (breakdown of red blood cells), leading to anemia, jaundice, or kidney damage.

⚪️Pregnancy

Why: The effects of ozone on a developing fetus are unknown. Safety cannot be guaranteed, so it’s avoided.

⚪️Severe anemia

Why: Ozone therapy involves withdrawing and reinfusing blood. Low hemoglobin can make this risky and reduce oxygen-carrying capacity further.

⚪️Hemorrhage or bleeding disorders

Why: Blood manipulation can worsen bleeding or complicate clotting.

⚪️Severe cardiovascular instability (e.g., recent heart attack, unstable angina) Why: The therapy temporarily alters blood properties and circulation, which can stress a compromised heart.

⚪️Hyperthyroidism

Why: Ozone can stimulate metabolism and circulation, potentially worsening symptoms.

⚪️Thrombocytopenia (low platelets)

Why: Increases risk of bleeding during blood withdrawal/reinfusion.

⚪️Severe kidney or liver failure

Why: The body may struggle to handle oxidative stress or clear byproducts.

⚪️Recent stroke or acute infection

Why: Circulatory stress and immune stimulation could be harmful during acute illness.

⚪️Seizure Disorders

Why: Ozone therapy causes mild oxidative stress and can temporarily change blood oxygenation and circulation. In some individuals with a seizure disorder, this might theoretically trigger a seizure, especially if their condition is poorly controlled.

⚪️Leukemia

Why: It is mainly due to blood cell fragility and immune compromise.

⚪️Other:

Known Allergy to Heparin or Sodium Citrate (Blood Thinners)

Known Allergy to Ozone

Alcohol Intoxication

While MAH ozone therapy is generally considered safe when performed by an experienced practitioner, patients may experience a range of side effects classified as common, transient, or rare but serious:

⚪️Common / Mild Side Effects

These are usually short-lived and resolve quickly:

• Fatigue or mild tiredness after the session

• Headache

• Light dizziness or feeling “spacey”

• Mild flu-like symptoms (especially if there’s a Herxheimer reaction)

• Temporary redness or mild bruising at the blood draw siteInjection‑site bruising, redness, or discomfort

• Dark or black/red urine following IV ozone treatments—likely due to the body mobilizing toxins or metabolites during the detoxification process (“healing crisis”).

⚪️Less Common / Moderate Side Effects

• Nausea or digestive upset

• Muscle or joint aches

• Transient changes in blood pressure (rare)

• Respiratory irritation (cough, chest tightness), especially if ozone is accidentally inhaled

• Vein inflammation or phlebitis

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⚪️Very Rare / Serious Side Effects

• Air embolism (extremely rare if protocol is followed correctly)

• Serious vascular events such as pulmonary embolism, stroke, or even myocardial infarction.

• Allergic reaction to anticoagulant or equipment (very uncommon)

Why side effects occur

• Most side effects are due to mild oxidative stress and the body’s detoxification response.

• Reactions like fatigue or flu-like symptoms often indicate the body is clearing toxins or activating the immune system.

• Proper dosing, slow infusion, and screening for contraindications minimize risks.